How Strong Is Fentanyl Compared to Other Opioids?

  • Fentanyl vs Dilaudid: Dilaudid, containing hydromorphone, is about 10 times more potent than morphine but still about one-tenth as strong as fentanyl.
  • Fentanyl vs Oxycodone: Oxycodone is about one-and-a-half times more potent than morphine, making it much weaker compared to fentanyl. Fentanyl’s potency is such that even a small amount can lead to overdose, significantly stronger than oxycodone and other commonly prescribed opioids.

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